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First published on May 22, 2008, doi:10.1177/0009922808315211

Clinical Pediatrics 2008;47:659.

A more recent version of this article appeared on September 1, 2008


Article

Transdermal Patch Medication Delivery Systems and Pediatric Poisonings, 2002-2006

Dina Parekh, Michael A. Miller*, Doug Borys, Paresh R. Patel, and Marc E. Levsky

* To whom correspondence should be addressed. E-mail: michael.adam.miller{at}us.army.mil.


   Abstract
Transdermal drug delivery systems are an increasingly popular method of medication delivery containing large quantities of medication and presenting new opportunities for toxicity. To provide a description of exposures to transdermal medications in a pediatric population, we studied exposures in individuals less than 12 years of age. This is a retrospective database study in which the Texas Poison Center Network database from 2002 to 2006 was reviewed. In all, 336 poison control center records of patch exposures over the 5-year period were identified. Of those, 110 cases involved children less than 12 years old. A majority of cases resulted in no significant clinical effects. One death resulted from opioid toxicity. Although a majority of patch exposures in children less than 12 years of age resulted in no significant clinical toxicity, practitioners and the public must be made aware of the available patch-based medications and their potential for toxicity in children.


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